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Heterosynaptic eLTD takes place at synapses adjacent for the stimulated synapses. Such as, stimulation of Schaffer collaterals in hippocampal CA1 contributes to a persistent minimize in GABAergic inhibition of CA1 pyramidal neurons (106). The system of eLTD at hippocampal inhibitory synapses appears to have to have inhibition of adenylyl cyclase an